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Narcolepsy vs. Chronic Fatigue Syndrome: Symptoms, Differences and Treatment


Published on 2025-03-19 20:43:19 - CNET
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  • People often confuse narcolepsy and chronic fatigue syndrome, but these are the differences you should pay attention to.

The article from CNET discusses the differences and similarities between narcolepsy and chronic fatigue syndrome (CFS), two conditions often confused due to overlapping symptoms like excessive daytime sleepiness. Narcolepsy is characterized by sudden sleep attacks, cataplexy (sudden muscle weakness often triggered by emotions), sleep paralysis, and hallucinations. It's caused by a deficiency in the neurotransmitter hypocretin, which regulates wakefulness. Treatment for narcolepsy includes medications like stimulants for wakefulness, antidepressants for cataplexy, and lifestyle adjustments. On the other hand, CFS, also known as myalgic encephalomyelitis (ME), involves profound fatigue not alleviated by rest, post-exertional malaise, and cognitive difficulties, but does not typically include the sleep-related symptoms like cataplexy. The cause of CFS is less understood, potentially involving immune system dysfunction, viral infections, or stress. Management of CFS focuses on symptom relief through pacing activities, cognitive behavioral therapy, and sometimes medications for pain or sleep issues. The article emphasizes the importance of accurate diagnosis due to the different treatment approaches for each condition.

Read the Full CNET Article at:
[ https://www.cnet.com/health/sleep/narcolepsy-chronic-fatigue-syndrome-symptoms-differences-treatment/ ]
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